In Conclusion!

Now we see that our immune system has a relationship with microbial exposure, and to decrease any form of microbial exposure will be hostile to us.  Allergy prevention is still a rising issue, and we are left open ended concerning what to do with our hypothesis.  Scientist have still yet to give an explanation about why all the concerning diseases are accumulating over the past few decades.  We are simply left with assuming statements, and concerns with our personal hygiene.  In conclusion, more studies need to be done which reveal more evidence of the “relationship” between microbial exposures and allergy, asthma, and auto immune diseases concerning our immune system.  New sciences that could reveal more evidence are: molecular evolutionary biology and population genetics.  More studies in these two key subjects will shed more light on the hygiene hypothesis.

 

Cause-and-Effect Schematic for the Hygiene Hypothesis

 

-          This diagram shows the relationship between microbial exposures, immune responses, and disease outcomes. The diagram indicates the genetic variables cause different immune responses and disease outcomes. Still left open ended are the genetic variables which modify responses and the outcomes.

 

 

 

 

References:

1.        Manuela, Clerici, Sironi, Mario. "The Hygiene Hypothesis: An Evolutionary Perspective." N.p., June 2010. Web. 25 Nov. 2012. <http://ehis.ebscohost.com/ehost/detail?sid=1adb4e1b-2ade-4a66-927b-934e3f014703%40sessionmgr111&vid=6&bk=1&hid=101&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#db=a9h&AN=51256404>.

2.       Murphy, Liu, James, Andrew. "Hygiene Hypothesis: Fact or Fiction?" ScienceDirect. Journal of Allergy and Clinical Immunology, n.d. Web. 25 Nov. 2012. <http://www.sciencedirect.com/science/article/pii/S0091674902914910>.

3.       Ring, Kramer, Behdrendt. "A Critical Approach to the Hygiene Hypothesis." A Critical Approach to the Hygiene Hypothesis. N.p., Dec. 2004. Web. 25 Nov. 2012. <http://ehis.ebscohost.com/ehost/detail?vid=3&hid=101&sid=5a9cab5c-e119-4ddd-a86b-db58b903571d%40sessionmgr110&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#db=a9h&AN=15373631>.