Hygiene Hypo

Should doctors limit the use of antibiotics in the early stages of human development?

This question should be considered as we become more familiar with rise of autoimmune diseases via The Hygiene Hypothesis. As we look into early exposure to germs during the most vital growth period of human beings we relate our research on laboratory experiments on mice. As we have observed with people in the more or less populated and cleanly environments, scientist put the hypothesis to the test with mice. Does early exposure to bacteria effect autoimmune disease in the adult stage? With two sample groups of mice, one raised in a germ free environment and other in a normal environment, the result showed proof. Allergies, asama, and other autoimmune diseases were developed in the germ free mice. Researched looked closer and saw killer T cells that normally fight off infection were becoming over active and actually targeted healthy tissue. This resulted in inflammation of lungs and in the colon in the germ free, "healthier" mice. Therefore the normal mice were examined showing healthier, normal signs of growth and life. 

Kawasaki disease is a prime example of allergic malfunction that was formed in humans through the failed exposure of microbes.  On a closer level Kawasaki is caused by inflammation and the "split" in the T cells resulting in immune defect.  While there is a substantially low rate of Kawasaki in indigenous Australians, the industrialized populations show a rise.  The results of the Kawasaki disease are of the same comparison with the mice laboratory experiments, also showing proof of a more vital immune system in the native, more natural children opposed to the high rise exposure in the industrialized children.

Work Cited:

VOALearningEnglish. "Why Getting Dirty Can Be Healthy for Children." YouTube. YouTube, 01 May 2012. Web. 07 Nov. 2012. http://www.youtube.com/watch?v=o6yt9wR64B4.

"Login-Library Resources." Login-Library Resources. N.p., Nov. 2011. Web. 07 Nov. 2012. <http://libproxy.uta.edu/ehost/pdfviewer/pdfviewer?sid=806f7f03-f8ea-401b-ba14-b3ceb7fce7cf@sessionmgr15>.